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醋酸地加瑞克 Degarelix acetate CAS:214766-78-6

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产品名称: 醋酸地加瑞克 Degarelix acetate CAS:214766-78-6
产品型号: C13549
产品展商: Chembest
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简单介绍

Degarelix acetate(FE-200486)


醋酸地加瑞克 Degarelix acetate CAS:214766-78-6  的详细介绍
醋酸地加瑞克

Product Name:Degarelix acetate(FE-200486)
 
CAS No.:214766-78-6
 
Synonym:FE-200486;FE200486;Firmagon
 
Chemical name:N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-[2,6-dioxohexahydropyrimidin-4(S)-ylcarboxamido]-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetate
 
Molecular formula:C82H103CLN18O16
 
Molecular weight:1632.28
  
Purity(HPLC):≥98%

Biological Activity:
Degarelix Acetate is an LHRH (GnRH) receptor antagonist, indicated for patients with advanced prostate cancer. Degarelix reversibly and dose-dependently suppresses gonadotropin and sex steroid levels by inhibiting the binding of endogenous LHRH to its receptors.
Degarelix showed to be at least as effective as leuprolide in sustaining levels of testosterone that are equivalent to or lower than that seen with castration. Degarelix or degarelix acetate(Firmagon) is a hormonal therapy used in the treatment of prostate cancer. During development it was known as FE200486.


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