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现货供应BEZ235(NVP-BEZ235)

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产品名称: 现货供应BEZ235(NVP-BEZ235)
产品型号: C13946
产品展商: Chembest
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简单介绍

Chemical Name: 2-Methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile 别名:NVP-BEZ235 分子式:C30H23N5O 分子量:469.55 纯度:>99% CAS:915019-65-7


现货供应BEZ235(NVP-BEZ235)  的详细介绍
Chemical Name: 2-Methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile
别名:NVP-BEZ235
分子式:C30H23N5O
分子量:469.55
纯度:>99%
CAS:915019-65-7
Biological Activity:
BEZ235 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BEZ235 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability; apoptotic cell death may ensue. Bax is a member of the proapoptotic Bcl2 family of proteins.
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