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现货供应Roscovitine/CYC202

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产品名称: 现货供应Roscovitine/CYC202
产品型号: C14123
产品展商: Chembest
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简单介绍

Chemical Name: (R)-Roscovitine; 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine Synonym: Seliciclib Molecular Formula: C19H26N6O Molecular Weight: 354.45 Purity: >98% CAS


现货供应Roscovitine/CYC202  的详细介绍
Chemical Name: (R)-Roscovitine; 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
Synonym: Seliciclib
Molecular Formula:  C19H26N6O
Molecular Weight:  354.45
Purity: >98%
CAS No.: 186692-46-6
Biological Activity:
Roscovitine is a cell permeable reversible selective inhibitor of cyclin-dependent kinases CDK1 (cdc2), CDK2 and CDK5. A purine analog, this drug competes for the binding site of ATP in the catalytic cleft. Treatment of cultured cells with roscovitine can cause cell cycle arrest or apoptosis. The IC50 for cdc2 activity is 0.65 µM in vitro.
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