产品资料

现货供应Varespladib(LY315920,LY-333013)/伐瑞拉迪对照品

如果您对该产品感兴趣的话,可以
产品名称: 现货供应Varespladib(LY315920,LY-333013)/伐瑞拉迪对照品
产品型号: C13850
产品展商: Chembest
产品文档: 无相关文档

简单介绍

标准品Varespladib(LY315920,LY-333013)/伐瑞拉迪 分子式:C21H20N2O5 分子量: 380.40 纯度: >99% CAS No: 172732-68-2


现货供应Varespladib(LY315920,LY-333013)/伐瑞拉迪对照品  的详细介绍
别名: 伐瑞拉迪对照品
英文名:Varespladib(LY315920,LY-333013)
Chemical Name:  [[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
分子式:C21H20N2O5
分子量: 380.40
Appearance:White powder
Solubility:Soluble in DMSO
纯度: >99%
储存条件: at -20℃ 2 years
CAS No: 172732-68-2
Biological Activity:
Varespladib is a selective inhibitor of human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic isolated enzyme assay, Varespladib inhibited sPLA2 activity with an IC50 of 9 6 ±1 nM or 7.3 *10-6 mole fraction, which approached the stiochiometric limit of this assay.Varespladib was 40-fold less active against human, group IB, pancreatic sPLA2 and was inactive against cytosolic PLA2 and the constitutive and inducible forms of cyclooxygenase.Human sPLA2-induced release of thromboxane A2 (TXA2) from isolated guinea pig lung bronchoalveolar lavage cells was inhibited by Varespladib with an IC50 of 0.79 nM. Therefore£¬the use of Varespladib have a beneficial effect in preventing various inflammatory disease states.

产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
产品与服务
订购指南
售后服务
联系我们

电邮: sales@Biochembest.com
订购热线: 021-20908456
QQ: 2885123256 (高校及科研院所客户)
QQ: 2885271621 (企业客户)