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Podophyllotoxin CAS:518-28-5

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产品名称: Podophyllotoxin CAS:518-28-5
产品型号: C11819
产品展商: Chembest
产品文档: 无相关文档

简单介绍

中文名称:鬼臼毒素; (5R,5aR,8aR,9R)-5R-5,8,8a,9-四氢-9-羟-5-(3,4,5-三甲氧苯基)呋喃(3',4':6,7)萘并-[2,3-d]-1,3-间二氧杂环烯-6(5aH)-酮 英文名称:Podophyllotoxin CAS:518-28-5


Podophyllotoxin CAS:518-28-5  的详细介绍
中文名称:鬼臼毒素; (5R,5aR,8aR,9R)-5R-5,8,8a,9-四氢-9-羟-5-(3,4,5-三甲氧苯基)呋喃(3',4':6,7)萘并-[2,3-d]-1,3-间二氧杂环烯-6(5aH)-酮
英文名称:Podophyllotoxin
产品别名:Podophyllinic acid lactone; (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS:518-28-5
分子式:C22H22O8
分子量:414.41

生物活性:
Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II.
IC50 Value:
Target: Topoisomerase II; Microtubule/Tubulin
Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use.
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