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现货供应对照品Agomelatine/阿戈美拉汀

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产品名称: 现货供应对照品Agomelatine/阿戈美拉汀
产品型号: C13263
产品展商: Chembest
产品文档: 无相关文档

简单介绍

别名:N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide 英文名:Agomelatine 分子式:C15H17NO2 分子量: 243.3 纯度: >99% 外观:White or almost white powder CAS No: 138112-76-2


现货供应对照品Agomelatine/阿戈美拉汀  的详细介绍

别名:N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide/N-[2-(7-甲氧基萘-1-基)乙基]乙酰胺

英文名:Agomelatine

分子式:C15H17NO2

分子量: 243.3
纯度:  >99%
外观:White or almost white powder

CAS No138112-76-2
Biological Activity: 
Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in an enhancement of DA and NE release and activity of frontocortical dopaminergic and adrenergic pathways. Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant.

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