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现货供应埃坡霉素B/Epothilone B(Patupilone)

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产品名称: 现货供应埃坡霉素B/Epothilone B(Patupilone)
产品型号: C13626
产品展商: Chembest
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简单介绍

中文名称:埃坡霉素B 英文名称:Epothilone B(Patupilone) 别名:EPO906,EpoB,Patupilone CAS NO.:152044-54-7


现货供应埃坡霉素B/Epothilone B(Patupilone)  的详细介绍

中文名称:埃坡霉素B
英文名称:Epothilone B(Patupilone)
别名:EPO906,EpoB,Patupilone
化学名称:(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
CAS NO.:152044-54-7
分子式:C27H41NO6S
分子量:507.68
外观:Colorless crystals
纯度:>99%
Usage: A compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Epothilone B may cause complete cell-cycle arrest.
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