产品资料

现货供应Vatalanib 2hcl/瓦他拉尼

如果您对该产品感兴趣的话,可以
产品名称: 现货供应Vatalanib 2hcl/瓦他拉尼
产品型号: C14321
产品展商: Chembest
产品文档: 无相关文档

简单介绍

别名:瓦他拉尼二盐酸盐; N-(4-氯苯基)-4-(4-吡啶甲基)-1-酞嗪胺二盐酸盐 化学名称:N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride 英文名:Vatalanib dihydrochloride 分子式: C20H15ClN4.2(HCl) 分子量: 419.74 纯度: >99% 外观


现货供应Vatalanib 2hcl/瓦他拉尼  的详细介绍
别名:瓦他拉尼二盐酸盐; N-(4-氯苯基)-4-(4-吡啶甲基)-1-酞嗪胺二盐酸盐
化学名称:N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride
英文名:Vatalanib dihydrochloride
分子式: C20H15ClN4.2(HCl)
分子量: 419.74
纯度: >99%
外观:White to off-white powder
CAS No: 212141-51-0
Biological Activity:
 
 
 
Vatalanib is a potent, selective, orally active inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC50 = 77 nM) and VEGFR-2 (FLK-1/KDR, IC50 = 37 nM), with slightly higher potency against the latter. At higher concentrations, other tyrosine kinases are also inhibited, including PDGFR-ß (IC50 = 580 nM), c-KIT (IC50 = 730 nM), FLT-4 (IC50 = 660 nM) and c-FMS (IC50 = 1.4 µM). On the other hand, vatalanib is not active against the EGFR, c-SRC, v-ABL, and protein kinase Cα (IC50 > 10 µM)
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
产品与服务
订购指南
售后服务
联系我们

电邮: sales@Biochembest.com
订购热线: 021-20908456
QQ: 2885123256 (高校及科研院所客户)
QQ: 2885271621 (企业客户)